James Giles

Instructor, Stroke Neurology
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I am an Instructor in Neurology at Washington University School of Medicine. Originally from the UK, I moved to St. Louis after medical school for neurology residency. I completed my PhD in 2012 investigating mechanisms of neurovascular inflammation. Since moving to St. Louis, I have developed a strong interest in clinical stroke research. I am currently focused on research into the implementation of evidence-based practice within stroke medicine, and am building an interdisciplinary research program that focuses on use of informatics tools to better support stroke care.

Positions

Instructor, Neurology

Washington University in St. Louis | 2018 - Present

I am junior research faculty in the Division of Vascular Neurology at Washington University. I am currently funded by NIH StrokeNet. I completed a Population Health Masters in 2020. My research focuses on implementation of informatics tools to support evidence-based practice in stroke medicine.

    Clinical Fellow, Neurovascular Disease

    University of Oxford | 2020 - 2021

    I was a Clinical Fellow at the Centre for the Prevention of Stroke and Dementia within the Nuffield Department of Clinical Neurosciences. I was a subinvestigator on the Oxford Vascular Study, with a focus on stroke risk with posterior circulation atherosclerosis.

      Current Projects

      The Adapted SPHERE Tool for Secondary Stroke Prevention

      2020-Present

      Clinical Trials

      2018-Present

      Oxford Vascular Study

      2020-Present

      Publication Highlights

      Peer-Reviewed Articles

      • Giles JA, Greenhalgh AD, Denes A, Nieswandt B, et al. Neutrophil Infiltration to the Brain Is Platelet-Dependent, and Is Reversed by Blockade of Platelet GPIba. Immunology. 2018;154(2):322–8. Pubmed
      • Yaghi S, Trivedi T, Henninger N, Giles JA, et al. Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk. Ann Neurol. 2020;88(4):807–16. Pubmed
      • Google Scholar Profile